Inggar Armytasari
Gadjah Mada University, Indonesia
Title: ASSOCIATION BETWEEN CLINICAL SIGN AND COLORECTAL MUCOSAL LESION SEVERITY IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE
Biography
Biography: Inggar Armytasari
Abstract
Inflammatory bowel disease (IBD) is an idiopathic inflammatoric disease in gastrointestinal tract. The clinical signs of IBD include chronic diarrhea, with or without mucous and/or with or without rectal bleeding. It hasn’t surely been known that there is a positive correlation between clinical sign and colorectal mucosal lesion severity in the IBD patients.
This study aims to determine the relationship between clinical sign in inflammatory bowel disease patients with the varying colorectal mucosal lesion. The study was conducted in a retrospective cross sectional using the medical records data from both inpatient dan outpatient with IBD in Sardjito General Hospital from January 2012 until July 2014.
From 65 data (42 men, 23 women, age 18 to 97 years old (49,94±18,25)), there is an insignificant weak positive correlation between clinical signs and lesion severity in IBD (p=0,0916, r=0,211), also in proctitis (p=0,1543, r=0,2876). Meanwhile in left-sided colitis, the correlation is insignificant and has a very weak positive correlation (p=0,9518, r=0,0125).
The only significant and stronger correlation is the correlation between rectal bleeding and lesion severity in the proctitis patients with p=0,0053 and r=0,5310.
So it can be concluded that there is an insignificant weak positive correlation between clinical signs and lesion severity in IBD, except for the proctitis where the correlation between rectal bleeding and lesion severuty is rather high. From this conclusion we can assume that clinical signs only cannot reflect the diseasse severuty of IBD, with the exception of proctitis where the eseverity of rectal bleeding can also depict the severity of the lesion.